MLN4924 Treatment Diminishes Excessive Lipid Storage in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease (NAFLD) by Stimulating Hepatic Mitochondrial Fatty Acid Oxidation and Lipid Metabolites

• Автори: Mengxiao Ge (Автор), Linlin Huang (Автор), Yinjun Ma (Автор), Shuangyi Sun (Автор), Lijun Wu (Автор), Wei Xu (Автор), Dongqin Yang (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2022-11-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

MLN4924 is a selective neddylation inhibitor that has shown great potential in treating several cancer and metabolic diseases, including obesity. However, it remains largely unknown whether MLN4924 has similar effect on non-alcoholic liver disease (NAFLD), which is closely associated with metabolic...