Synergy effects of Polyinosinic-polycytidylic acid, CpG oligodeoxynucleotide, and cationic peptides to adjuvant HPV E7 epitope vaccine through preventive and therapeutic immunization in a TC-1 grafted mouse model

• Main Authors: Cunbao Liu (Author), Xiaojie Chu (Author), Pengyan Sun (Author), Xuejun Feng (Author), Weiwei Huang (Author), Hongxian Liu (Author), Yanbing Ma (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cross-talk by pattern recognition receptors may facilitate the maturation of dendritic cells and fine tune the immune response. Thus, the inclusion of ligands agonistic to multiple receptors in a vaccine formula may be an effective strategy to elicit robust antitumor cellular immunity. We tested the...