Synergy effects of Polyinosinic-polycytidylic acid, CpG oligodeoxynucleotide, and cationic peptides to adjuvant HPV E7 epitope vaccine through preventive and therapeutic immunization in a TC-1 grafted mouse model

• Κύριοι συγγραφείς: Cunbao Liu (Συγγραφέας), Xiaojie Chu (Συγγραφέας), Pengyan Sun (Συγγραφέας), Xuejun Feng (Συγγραφέας), Weiwei Huang (Συγγραφέας), Hongxian Liu (Συγγραφέας), Yanbing Ma (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2018-04-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Cross-talk by pattern recognition receptors may facilitate the maturation of dendritic cells and fine tune the immune response. Thus, the inclusion of ligands agonistic to multiple receptors in a vaccine formula may be an effective strategy to elicit robust antitumor cellular immunity. We tested the...