Novel 2-indolinones containing a sulfonamide moiety as selective inhibitors of candida β-carbonic anhydrase enzyme

Inhibition of the β-carbonic anhydrase (CA, EC 4.2.1.1) from pathogenic Candida glabrata (CgNce103) by 1H-indole-2,3-dione 3-[N-(4-sulfamoylphenyl)thiosemicarbazones] 4a-m was investigated. All the compounds were found to be potent inhibitors of CgNce103, with inhibition constants in the range of 6....

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Main Authors: Atilla Akdemir (Author), Andrea Angeli (Author), Füsun Göktaş (Author), Pınar Eraslan Elma (Author), Nilgün Karalı (Author), Claudiu T. Supuran (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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