Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann syndrome

• Ngā kaituhi matua: Simon J. Tunster (Author), Mathew Van de Pette (Author), Hugo D. J. Creeth (Author), Louis Lefebvre (Author), Rosalind M. John (Author)
• Hōputu: Pukapuka
• I whakaputaina: The Company of Biologists, 2018-11-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Beckwith-Wiedemann syndrome (BWS) is a complex imprinting disorder involving fetal overgrowth and placentomegaly, and is associated with a variety of genetic and epigenetic mutations affecting the expression of imprinted genes on human chromosome 11p15.5. Most BWS cases are linked to loss of methyla...