Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann syndrome

• Главные авторы: Simon J. Tunster (Автор), Mathew Van de Pette (Автор), Hugo D. J. Creeth (Автор), Louis Lefebvre (Автор), Rosalind M. John (Автор)
• Формат: ‌
• Опубликовано: The Company of Biologists, 2018-11-01T00:00:00Z.
• Предметы: article
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Beckwith-Wiedemann syndrome (BWS) is a complex imprinting disorder involving fetal overgrowth and placentomegaly, and is associated with a variety of genetic and epigenetic mutations affecting the expression of imprinted genes on human chromosome 11p15.5. Most BWS cases are linked to loss of methyla...