L-carnitine prevents lenvatinib-induced muscle toxicity without impairment of the anti-angiogenic efficacy

• المؤلفون الرئيسيون: Zheng Jing (مؤلف), Tomohiro Iba (مؤلف), Hisamichi Naito (مؤلف), Pingping Xu (مؤلف), Jun-ichi Morishige (مؤلف), Naoto Nagata (مؤلف), Hironao Okubo (مؤلف), Hitoshi Ando (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Lenvatinib is an oral tyrosine kinase inhibitor that acts on multiple receptors involved in angiogenesis. Lenvatinib is a standard agent for the treatment of several types of advanced cancers; however, it frequently causes muscle-related adverse reactions. Our previous study revealed that lenvatinib...