A novel peroxisome proliferator-activated receptor gamma ligand improves insulin sensitivity and promotes browning of white adipose tissue in obese mice

• 主要な著者: Dan Wu (著者), Venkateswararao Eeda (著者), Ram Babu Undi (著者), Shivani Mann (著者), Michael Stout (著者), Hui-Ying Lim (著者), Weidong Wang (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2021-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Objective: Nuclear receptor Peroxisome Proliferator-Activated Receptor γ (PPARγ) is a promising target for the treatment of type 2 diabetes. The antidiabetic drug thiazolidinediones (TZDs) are potent insulin sensitizers as full agonists of PPARγ, but cause unwanted side effects. Recent discoveries h...