Samotolisib Attenuates Acute Liver Injury Through Inhibiting Caspase-11-Mediated Pyroptosis Via Regulating E3 Ubiquitin Ligase Nedd4

Acute liver injury (ALI) is associated with poor survival in patients with sepsis. During sepsis, the liver is the main site of bacterial endotoxin-induced inflammation. Lipopolysaccharide (LPS) promotes caspase-4/5/11 activation, leading to pyroptosis, a major sepsis driver. This study aimed to ide...

Full description

Saved in:
Bibliographic Details
Main Authors: Yang-Yang Zhao (Author), Dong-Ming Wu (Author), Miao He (Author), Feng Zhang (Author), Ting Zhang (Author), Teng Liu (Author), Jin Li (Author), Li Li (Author), Ying Xu (Author)
Format: Book
Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available