Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma

• Váldodahkkit: Melanie J. Mittenbühler (Dahkki), Hans-Georg Sprenger (Dahkki), Sabine Gruber (Dahkki), Claudia M. Wunderlich (Dahkki), Lara Kern (Dahkki), Jens C. Brüning (Dahkki), F. Thomas Wunderlich (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2018-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Objective: The current obesity pandemic represents a major health burden, given that it predisposes to the development of numerous obesity-associated disorders. The obesity-derived adipokines not only impair systemic insulin action but also increase the incidence of hepatocellular carcinoma (HCC), a...