Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway

• Hoofdauteurs: Yingquan Liang (Auteur), Guilan Chen (Auteur), Feng Zhang (Auteur), Xiaoxiao Yang (Auteur), Yuanli Chen (Auteur), Yajun Duan (Auteur), Maoyun Yu (Auteur), Shuang Zhang (Auteur), Jihong Han (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2021-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Vascular calcification is strongly associated with atherosclerotic plaque burden and plaque instability. The activation of extracellular signal-regulated kinase 1/2 (ERK1/2) increases runt related transcription factor 2 (RUNX2) expression to promote vascular calcification. Procyanidin B2 (PB2), a po...