Methylphenidate Analogues as a New Class of Potential Disease-Modifying Agents for Parkinson's Disease: Evidence from Cell Models and Alpha-Synuclein Transgenic Mice

• Автори: Andrea Casiraghi (Автор), Francesca Longhena (Автор), Gaia Faustini (Автор), Giovanni Ribaudo (Автор), Lorenzo Suigo (Автор), Gisela Andrea Camacho-Hernandez (Автор), Federica Bono (Автор), Viviana Brembati (Автор), Amy Hauck Newman (Автор), Alessandra Gianoncelli (Автор), Valentina Straniero (Автор), Arianna Bellucci (Автор), Ermanno Valoti (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2022-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Parkinson's disease (PD) is characterized by dopaminergic nigrostriatal neurons degeneration and Lewy body pathology, mainly composed of α-synuclein (αSyn) fibrillary aggregates. We recently described that the neuronal phosphoprotein Synapsin III (Syn III) participates in αSyn pathology in PD b...