Relating Molecular Dynamics Simulations to Functional Activity for Gly-Rich Membranolytic Helical Kiadin Peptides

• Główni autorzy: Tomislav Rončević (Autor), Matko Maleš (Autor), Yogesh Sonavane (Autor), Filomena Guida (Autor), Sabrina Pacor (Autor), Alessandro Tossi (Autor), Larisa Zoranić (Autor)
• Format: Książka
• Wydane: MDPI AG, 2023-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Kiadins are in silico designed peptides with a strong similarity to <i>di</i>PGLa-H, a tandem sequence of PGLa-H (KIAKVALKAL) and with single, double or quadruple glycine substitutions. They were found to show high variability in their activity and selectivity against Gram-negative and G...