Mitoxantrone-Loaded Nanoparticles for Magnetically Controlled Tumor Therapy-Induction of Tumor Cell Death, Release of Danger Signals and Activation of Immune Cells

• Main Authors: Teresa Ratschker (Author), Laura Egenberger (Author), Magdalena Alev (Author), Lisa Zschiesche (Author), Julia Band (Author), Eveline Schreiber (Author), Benjamin Frey (Author), Anja Derer (Author), Christoph Alexiou (Author), Christina Janko (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stimulating the patient's immune system represents a promising therapeutic strategy to fight cancer. However, low immunogenicity of the tumor cells within an immune suppressive milieu often leads to weak anti-tumor immune responses. Additionally, the immune system may be impaired by accompanyin...