Mitoxantrone-Loaded Nanoparticles for Magnetically Controlled Tumor Therapy-Induction of Tumor Cell Death, Release of Danger Signals and Activation of Immune Cells

• Egile Nagusiak: Teresa Ratschker (Egilea), Laura Egenberger (Egilea), Magdalena Alev (Egilea), Lisa Zschiesche (Egilea), Julia Band (Egilea), Eveline Schreiber (Egilea), Benjamin Frey (Egilea), Anja Derer (Egilea), Christoph Alexiou (Egilea), Christina Janko (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2020-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Stimulating the patient's immune system represents a promising therapeutic strategy to fight cancer. However, low immunogenicity of the tumor cells within an immune suppressive milieu often leads to weak anti-tumor immune responses. Additionally, the immune system may be impaired by accompanyin...