Strong nuclear EGFR expression in colorectal carcinomas is associated with cyclin-D1 but not with gene EGFR amplification

• Hauptverfasser: Dekanić Andrea (Verfasst von), Dobrila Dintinjan Renata (Verfasst von), Budisavljević Ivana (Verfasst von), Pećanić Sanja (Verfasst von), Žuvić Butorac Marta (Verfasst von), Jonjić Nives (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2011-11-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Prognostic and predictive significance of epidermal growth factor receptor (EGFR) in colorectal carcinomas (CRCs) is still controversial. The aim of the present study was to explore and correlate membrane and nuclear EGFR and cyclin-...