Strong nuclear EGFR expression in colorectal carcinomas is associated with cyclin-D1 but not with gene EGFR amplification

• Main Authors: Dekanić Andrea (Author), Dobrila Dintinjan Renata (Author), Budisavljević Ivana (Author), Pećanić Sanja (Author), Žuvić Butorac Marta (Author), Jonjić Nives (Author)
• Format: Book
• Published: BMC, 2011-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Prognostic and predictive significance of epidermal growth factor receptor (EGFR) in colorectal carcinomas (CRCs) is still controversial. The aim of the present study was to explore and correlate membrane and nuclear EGFR and cyclin-...