A multiparametric approach to monitor the effects of γ-secretase inhibition along the whole intestinal tract
SUMMARY γ-secretase inhibitors (GSIs) have been recently proposed as chemopreventive agents in gastrointestinal neoplasia, because they lead, through inhibition of the Notch signaling pathway, to goblet cell conversion in some intestinal adenomas of the ApcMin mice, and halt epithelial cell prolifer...
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Format: | Book |
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The Company of Biologists,
2012-01-01T00:00:00Z.
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A1234.567 |
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