A multiparametric approach to monitor the effects of γ-secretase inhibition along the whole intestinal tract

SUMMARY γ-secretase inhibitors (GSIs) have been recently proposed as chemopreventive agents in gastrointestinal neoplasia, because they lead, through inhibition of the Notch signaling pathway, to goblet cell conversion in some intestinal adenomas of the ApcMin mice, and halt epithelial cell prolifer...

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Main Authors: Laure Droy-Dupré (Author), Mickaël Vallée (Author), Céline Bossard (Author), Christian L. Laboisse (Author), Anne Jarry (Author)
Format: Book
Published: The Company of Biologists, 2012-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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