Skin-Derived Precursor Cells as an In Vitro Modelling Tool for the Study of Type 1 Neurofibromatosis

• Main Authors: Araika Gutiérrez-Rivera (Author), Haizea Iribar (Author), Anna Tuneu (Author), Ander Izeta (Author)
• Formato: Livro
• Publicado em: Hindawi Limited, 2012-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The most characteristic feature of neurofibromatosis type 1 (NF1) is the development of neurofibromas. It has been suggested that these tumors are caused by somatic inactivation of the wild-type NF1 allele, but the cell that originally suffers this mutation remains controversial. Several lines of ev...