Skin-Derived Precursor Cells as an In Vitro Modelling Tool for the Study of Type 1 Neurofibromatosis

• Những tác giả chính: Araika Gutiérrez-Rivera (Tác giả), Haizea Iribar (Tác giả), Anna Tuneu (Tác giả), Ander Izeta (Tác giả)
• Định dạng: Sách
• Được phát hành: Hindawi Limited, 2012-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

The most characteristic feature of neurofibromatosis type 1 (NF1) is the development of neurofibromas. It has been suggested that these tumors are caused by somatic inactivation of the wild-type NF1 allele, but the cell that originally suffers this mutation remains controversial. Several lines of ev...