Potential role of glutathione in evolution of thiol-based redox signaling sites in proteins

• Główni autorzy: Kaavya A Mohanasundaram (Autor), Naomi L Haworth (Autor), Mani P Grover (Autor), Tamsyn M Crowley (Autor), Andrzej eGoscinski (Autor), Merridee Ann Wouters (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2015-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Cysteine is susceptible to a variety of modifications by reactive oxygen and nitrogen oxide species, including glutathionylation; and when two cysteines are involved, disulfide formation. Glutathione-cysteine adducts may be removed from proteins by glutaredoxin, whereas disulfides may be reduced by...