Irisin Is Controlled by Farnesoid X Receptor and Regulates Cholesterol Homeostasis

• मुख्य लेखकों: Hong Li (लेखक), Jing Shen (लेखक), Tong Wu (लेखक), Jiangying Kuang (लेखक), Qinhui Liu (लेखक), Shihai Cheng (लेखक), Shiyun Pu (लेखक), Lei Chen (लेखक), Rui Li (लेखक), Yanping Li (लेखक), Min Zou (लेखक), Zhiyong Zhang (लेखक), Wei Jiang (लेखक), Aijuan Qu (लेखक), Jinhan He (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

ObjectiveThe aim of this study was to investigate whether the nuclear receptor farnesoid X receptor (FXR) could regulate FNDC5/Irisin expression and the role of Irisin in hyperlipidemia and atherosclerosis in ApoE-/- mice.Methods and ResultsWe treated primary human hepatocytes, HepG2 cells, and Rhes...