Toxicokinetics of recombinant human fibroblast growth factor 21 for injection in cynomolgus monkey for 3 months

• Main Authors: Chao Lu (Author), Lei Jin (Author), Jianing Bi (Author), Hongyi Jin (Author), Xinyi You (Author), Lulu Peng (Author), Haibing Fan (Author), Huan Wang (Author), Liangshun Wang (Author), Zhengkai Fan (Author), Xiaojie Wang (Author), Baohua Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Recombinant human fibroblast growth factor 21 (FGF-21) is a potential therapeutic agent for multiple metabolic diseases. However, little is known about the toxicokinetic characteristics of FGF-21.Methods: In the present study, we investigated the toxicokinetics of FGF-21 delivered via...