Toxicokinetics of recombinant human fibroblast growth factor 21 for injection in cynomolgus monkey for 3 months

• मुख्य लेखकों: Chao Lu (लेखक), Lei Jin (लेखक), Jianing Bi (लेखक), Hongyi Jin (लेखक), Xinyi You (लेखक), Lulu Peng (लेखक), Haibing Fan (लेखक), Huan Wang (लेखक), Liangshun Wang (लेखक), Zhengkai Fan (लेखक), Xiaojie Wang (लेखक), Baohua Liu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: Recombinant human fibroblast growth factor 21 (FGF-21) is a potential therapeutic agent for multiple metabolic diseases. However, little is known about the toxicokinetic characteristics of FGF-21.Methods: In the present study, we investigated the toxicokinetics of FGF-21 delivered via...