Spatio-temporal delivery of both intra- and extracellular toll-like receptor agonists for enhancing antigen-specific immune responses

• 主要な著者: Nannan Wang (著者), Yueyue Zuo (著者), Shengjie Wu (著者), Chenlu Huang (著者), Linhua Zhang (著者), Dunwan Zhu (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2022-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

For cancer immunotherapy, triggering toll-like receptors (TLRs) in dendritic cells (DCs) can potentiate antigen-based immune responses. Nevertheless, to generate robust and long-lived immune responses, a well-designed nanovaccine should consider different locations of TLRs on DCs and co-deliver both...