Spatio-temporal delivery of both intra- and extracellular toll-like receptor agonists for enhancing antigen-specific immune responses

• Hoofdauteurs: Nannan Wang (Auteur), Yueyue Zuo (Auteur), Shengjie Wu (Auteur), Chenlu Huang (Auteur), Linhua Zhang (Auteur), Dunwan Zhu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2022-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

For cancer immunotherapy, triggering toll-like receptors (TLRs) in dendritic cells (DCs) can potentiate antigen-based immune responses. Nevertheless, to generate robust and long-lived immune responses, a well-designed nanovaccine should consider different locations of TLRs on DCs and co-deliver both...