Saffron offers hepatoprotection via up-regulation of hepatic farnesoid-X-activated receptors in a rat model of acetaminophen-induced hepatotoxicity

• 主要な著者: Vahid Jamshidi (著者), Seyed Ali Hashemi (著者), azadeh Khalili (著者), Parviz Fallah (著者), Mohammad Mahdi Ahmadian-Attari (著者), Leila Beikzadeh (著者), Roham Mazloom (著者), Parvaneh Najafizadeh (著者), Gholamreza Bayat (著者)
• フォーマット: 図書
• 出版事項: Mashhad University of Medical Sciences, 2021-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Objectives: The most important toxicity of acetaminophen is hepatotoxicity. Farnesoid X-activated receptors (FXR) are one of the nuclear receptor superfamily members which have a pivotal role in the bile acid regulation. The objective of the present study was to examine the role of FXR in mediating...