Mechanistic PK/PD modeling to address early-stage biotherapeutic dosing feasibility questions

ABSTRACTEarly assessment of dosing requirements should be an integral part of developability assessments for a discovery program. If a very high dose is required to achieve the desired pharmacological effect, it may not be clinically feasible or commercially desirable to develop the biotherapeutic f...

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Main Authors: Joshuaine Grant (Author), Fei Hua (Author), Joshua F. Apgar (Author), John M. Burke (Author), Diana H. Marcantonio (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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