Tertiary amine derivatives of chlorochalcone as acetylcholinesterase (AChE) and buthylcholinesterase (BuChE) inhibitors: the influence of chlorine, alkyl amine side chain and α,β-unsaturated ketone group

A new series of tertiary amine derivatives of chlorochalcone (4a∼4l) were designed, synthesized and evaluated for the effect on acetylcholinesterase (AChE) and buthylcholinesterase (BuChE). The results indicated that all compounds revealed moderate or potent inhibitory activity against AChE, and som...

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Main Authors: Xiao-hui Gao (Author), Chao Zhou (Author), Hao-ran Liu (Author), Lin-bo Liu (Author), Jing-jing Tang (Author), Xin-hua Xia (Author)
Formato: Livro
Publicado em: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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