ORY-1001 Suppresses Cell Growth and Induces Apoptosis in Lung Cancer Through Triggering HK2 Mediated Warburg Effect

ORY-1001 Suppresses Cell Growth and Induces Apoptosis in Lung Cancer Through Triggering HK2 Mediated Warburg Effect

ORY-1001, an inhibitor of covalent lysine (K)-specific demethylase 1A (KDM1A), has been used as a therapy for the treatment of acute leukemia. However, the underlying mechanisms of anticancer are still not fully elucidated. Here, we report that KDM1A is highly expressed in lung cancers, where it app...

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Main Authors: Zhaoliang Lu (Author), Yanke Guo (Author), Xiaoya Zhang (Author), Jing Li (Author), Leilei Li (Author), Shuai Zhang (Author), Changliang Shan (Author)
Format: Book
Published: Frontiers Media S.A., 2018-12-01T00:00:00Z.
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