Benserazide, a cystathionine beta-synthase (CBS) inhibitor, potentially enhances the anticancer effects of paclitaxel via inhibiting the S-sulfhydration of SIRT1 and the HIF1-α/VEGF pathway

Cancer targeted therapy is essential to minimize damage to normal cells and improve treatment outcomes. The elevated activity of Cystathionine beta-synthase (CBS), an enzyme responsible for producing endogenous hydrogen sulfide (H2S), plays a significant role in promoting tumor growth, invasiveness,...

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Main Authors: Wei Zhao (Author), Shasha Feng (Author), Jian Wang (Author), Zhenshuai Zhang (Author), Lu Chen (Author), Li Jiang (Author), Ming Li (Author), Tianxiao Wang (Author)
Format: Book
Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
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3rd Floor Main Library

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