Biomimetic Artificial Membrane Permeability Assay over Franz Cell Apparatus Using BCS Model Drugs

• Asıl Yazarlar: Leonardo de Souza Teixeira (Yazar), Tatiana Vila Chagas (Yazar), Antonio Alonso (Yazar), Isabel Gonzalez-Alvarez (Yazar), Marival Bermejo (Yazar), James Polli (Yazar), Kênnia Rocha Rezende (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2020-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

A major parameter controlling the extent and rate of oral drug absorption is permeability through the lipid bilayer of intestinal epithelial cells. Here, a biomimetic artificial membrane permeability assay (Franz-PAMPA Pampa) was validated using a Franz cells apparatus. Both high and low permeabilit...