Genetic polymorphisms in the endothelial nitric oxide synthase gene correlate with overall survival in advanced non-small-cell lung cancer patients treated with platinum-based doublet chemotherapy

• Asıl Yazarlar: Mio Tadashi (Yazar), Kim Young (Yazar), Kaji Reiko (Yazar), Hata Akito (Yazar), Fukuhara Akiko (Yazar), Hatachi Yukimasa (Yazar), Masago Katsuhiro (Yazar), Fujita Shiro (Yazar), Mishima Michiaki (Yazar), Katakami Nobuyuki (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2010-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Nitric oxide (NO) is a free radical that is involved in carcinogenesis. Endothelial NO, synthesized from L-arginine by endothelial NO synthase (eNOS), inhibits apoptosis and promotes angiogenesis, tumor cell proliferation and metasta...