Genetic polymorphisms in the endothelial nitric oxide synthase gene correlate with overall survival in advanced non-small-cell lung cancer patients treated with platinum-based doublet chemotherapy

• প্রধান লেখক: Mio Tadashi (লেখক), Kim Young (লেখক), Kaji Reiko (লেখক), Hata Akito (লেখক), Fukuhara Akiko (লেখক), Hatachi Yukimasa (লেখক), Masago Katsuhiro (লেখক), Fujita Shiro (লেখক), Mishima Michiaki (লেখক), Katakami Nobuyuki (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2010-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Nitric oxide (NO) is a free radical that is involved in carcinogenesis. Endothelial NO, synthesized from L-arginine by endothelial NO synthase (eNOS), inhibits apoptosis and promotes angiogenesis, tumor cell proliferation and metasta...