Augmentation of EPR Effect and Efficacy of Anticancer Nanomedicine by Carbon Monoxide Generating Agents

• Главные авторы: Jun Fang (Автор), Rayhanul Islam (Автор), Waliul Islam (Автор), Hongzhuan Yin (Автор), Vladimir Subr (Автор), Tomas Etrych (Автор), Karel Ulbrich (Автор), Hiroshi Maeda (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2019-07-01T00:00:00Z.
• Предметы: article
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One obstacle to the successful delivery of nanodrugs into solid tumors is the heterogeneity of an enhanced permeability and retention (EPR) effect as a result of occluded or embolized tumor blood vessels. Therefore, the augmentation of the EPR effect is critical for satisfactory anticancer nanomedic...