Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology

• Main Authors: Nandini Singh (Author), Tara Dutka (Author), Benjamin M. Devenney (Author), Kazuhiko Kawasaki (Author), Roger H. Reeves (Author), Joan T. Richtsmeier (Author)
• Format: Book
• Published: The Company of Biologists, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hedgehog (HH) signaling, and particularly signaling by sonic hedgehog (SHH), is implicated in several essential activities during morphogenesis, and its misexpression causes a number of developmental disorders in humans. In particular, a reduced mitogenic response of cerebellar granule cell precurso...