Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology

• Principais autores: Nandini Singh (Autor), Tara Dutka (Autor), Benjamin M. Devenney (Autor), Kazuhiko Kawasaki (Autor), Roger H. Reeves (Autor), Joan T. Richtsmeier (Autor)
• Formato: Livro
• Publicado em: The Company of Biologists, 2015-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Hedgehog (HH) signaling, and particularly signaling by sonic hedgehog (SHH), is implicated in several essential activities during morphogenesis, and its misexpression causes a number of developmental disorders in humans. In particular, a reduced mitogenic response of cerebellar granule cell precurso...