Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway

• 主要な著者: Can Hu (著者), Xin Zhang (著者), Wenying Wei (著者), Ning Zhang (著者), Haiming Wu (著者), Zhenguo Ma (著者), Lingli Li (著者), Wei Deng (著者), Qizhu Tang (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2019-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Oxidative stress and cardiomyocyte apoptosis are involved in the pathogenesis of doxorubicin (DOX)-induced cardiotoxicity. Matrine is well-known for its powerful anti-oxidant and anti-apoptotic capacities. Our present study aimed to investigate the effect of matrine on DOX-induced cardiotoxicity and...