Tenovin-1 Ameliorates Renal Fibrosis in High-Fat-Diet-Induced Diabetic Nephropathy via Antioxidant and Anti-Inflammatory Pathways

• Главные авторы: Amit Kundu (Автор), Sreevarsha Gali (Автор), Swati Sharma (Автор), Jae Hyeon Park (Автор), So Young Kyung (Автор), Sam Kacew (Автор), In Su Kim (Автор), Kwang Youl Lee (Автор), Hyung Sik Kim (Автор)
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• Опубликовано: MDPI AG, 2022-09-01T00:00:00Z.
• Предметы: article
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High-fat diet (HFD)-induced obesity has been involved in the development of diabetic nephropathy (DN). Tenovin-1, a potent selective SIRT1/2 inhibitor, regulates various target proteins. The present study evaluated the protective effect of Tenovin-1 against renal fibrosis in HFD-induced Zucker diabe...