Tenovin-1 Ameliorates Renal Fibrosis in High-Fat-Diet-Induced Diabetic Nephropathy via Antioxidant and Anti-Inflammatory Pathways

• मुख्य लेखकों: Amit Kundu (लेखक), Sreevarsha Gali (लेखक), Swati Sharma (लेखक), Jae Hyeon Park (लेखक), So Young Kyung (लेखक), Sam Kacew (लेखक), In Su Kim (लेखक), Kwang Youl Lee (लेखक), Hyung Sik Kim (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

High-fat diet (HFD)-induced obesity has been involved in the development of diabetic nephropathy (DN). Tenovin-1, a potent selective SIRT1/2 inhibitor, regulates various target proteins. The present study evaluated the protective effect of Tenovin-1 against renal fibrosis in HFD-induced Zucker diabe...