Long Noncoding RNA lnc-HC Regulates PPARγ-Mediated Hepatic Lipid Metabolism through miR-130b-3p

• Main Authors: Xi Lan (Author), Litao Wu (Author), Nan Wu (Author), Qian Chen (Author), Yue Li (Author), Xiaojuan Du (Author), Chenxi Wei (Author), Lina Feng (Author), Yazhao Li (Author), Ezra Kombo Osoro (Author), Mengyao Sun (Author), Qilan Ning (Author), Xiaofei Yan (Author), Xudong Yang (Author), Dongmin Li (Author), Shemin Lu (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nonalcoholic fatty liver disease (NAFLD) is due to the excessive lipid accumulation within hepatocytes. Metabolic nuclear receptors (MNRs) play great roles in lipid homeostasis. We have identified a novel long noncoding RNA (lncRNA), lnc-HC, which regulates hepatocytic cholesterol metabolism through...