Long Noncoding RNA lnc-HC Regulates PPARγ-Mediated Hepatic Lipid Metabolism through miR-130b-3p

• Главные авторы: Xi Lan (Автор), Litao Wu (Автор), Nan Wu (Автор), Qian Chen (Автор), Yue Li (Автор), Xiaojuan Du (Автор), Chenxi Wei (Автор), Lina Feng (Автор), Yazhao Li (Автор), Ezra Kombo Osoro (Автор), Mengyao Sun (Автор), Qilan Ning (Автор), Xiaofei Yan (Автор), Xudong Yang (Автор), Dongmin Li (Автор), Shemin Lu (Автор)
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• Опубликовано: Elsevier, 2019-12-01T00:00:00Z.
• Предметы: article
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Nonalcoholic fatty liver disease (NAFLD) is due to the excessive lipid accumulation within hepatocytes. Metabolic nuclear receptors (MNRs) play great roles in lipid homeostasis. We have identified a novel long noncoding RNA (lncRNA), lnc-HC, which regulates hepatocytic cholesterol metabolism through...