Cyclodextrin Complexation as a Way of Increasing the Aqueous Solubility and Stability of Carvedilol

Cyclodextrin Complexation as a Way of Increasing the Aqueous Solubility and Stability of Carvedilol

We studied the effect of several CDs on carvedilol's solubility and chemical stability in various aqueous media. Our present results show that it is possible to achieve a carvedilol concentration of 5 mg/mL (12.3 mM) in the presence of 5 eq of γCD or RAMEB in an aqueous medium with an acceptabl...

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Main Authors: Sébastien Rigaud (Author), David Mathiron (Author), Tarek Moufawad (Author), David Landy (Author), Florence Djedaini-Pilard (Author), Frédéric Marçon (Author)
Format: Book
Published: MDPI AG, 2021-10-01T00:00:00Z.
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