Inhibition of IL-17 signaling in macrophages underlies the anti-arthritic effects of halofuginone hydrobromide: Network pharmacology, molecular docking, and experimental validation

• Asıl Yazarlar: Junping Zhu (Yazar), Jiaming Wei (Yazar), Ye Lin (Yazar), Yuanyuan Tang (Yazar), Zhaoli Su (Yazar), Liqing Li (Yazar), Bin Liu (Yazar), Xiong Cai (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2024-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background Rheumatoid arthritis (RA) is a prevalent autoimmune disease marked by chronic synovitis as well as cartilage and bone destruction. Halofuginone hydrobromide (HF), a bioactive compound derived from the Chinese herbal plant Dichroa febrifuga Lour., has demonstrated substantial anti...