Inhibition of IL-17 signaling in macrophages underlies the anti-arthritic effects of halofuginone hydrobromide: Network pharmacology, molecular docking, and experimental validation

• প্রধান লেখক: Junping Zhu (লেখক), Jiaming Wei (লেখক), Ye Lin (লেখক), Yuanyuan Tang (লেখক), Zhaoli Su (লেখক), Liqing Li (লেখক), Bin Liu (লেখক), Xiong Cai (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2024-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background Rheumatoid arthritis (RA) is a prevalent autoimmune disease marked by chronic synovitis as well as cartilage and bone destruction. Halofuginone hydrobromide (HF), a bioactive compound derived from the Chinese herbal plant Dichroa febrifuga Lour., has demonstrated substantial anti...