Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish

• Үндсэн зохиолчид: Wenqing Zhou (Зохиогч), Lingyan Cao (Зохиогч), Jacob Jeffries (Зохиогч), Xiaoguang Zhu (Зохиогч), Christopher J. Staiger (Зохиогч), Qing Deng (Зохиогч)
• Формат: Ном
• Хэвлэсэн: The Company of Biologists, 2018-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Neutrophils are fast-moving cells essential for host immune functions. Although they primarily rely on glycolysis for ATP, isolated primary human neutrophils depend on mitochondrial membrane potential for chemotaxis. However, it is not known whether mitochondria regulate neutrophil motility in vivo,...