Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish

• 主要な著者: Wenqing Zhou (著者), Lingyan Cao (著者), Jacob Jeffries (著者), Xiaoguang Zhu (著者), Christopher J. Staiger (著者), Qing Deng (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2018-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Neutrophils are fast-moving cells essential for host immune functions. Although they primarily rely on glycolysis for ATP, isolated primary human neutrophils depend on mitochondrial membrane potential for chemotaxis. However, it is not known whether mitochondria regulate neutrophil motility in vivo,...