Sinomenine Attenuates Angiotensin II-Induced Autophagy via Inhibition of P47-Phox Translocation to the Membrane and Influences Reactive Oxygen Species Generation in Podocytes

• Үндсэн зохиолчид: Weili Wang (Зохиогч), Juan Cai (Зохиогч), Sha Tang (Зохиогч), Ying Zhang (Зохиогч), Xuejing Gao (Зохиогч), Lijiao Xie (Зохиогч), Zhirong Mou (Зохиогч), Yuzhang Wu (Зохиогч), Li Wang (Зохиогч), Jingbo Zhang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Karger Publishers, 2016-02-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Background/Aims: Sinomenine, a pure alkaloid extracted from the Chinese medicinal plant Sinomenium acutum, and sinomenine hydrochloride (SN) has been successfully used for the therapy of rheumatoid arthritis (RA) and kidney diseases. Autophagy is a cytoprotective mechanism used by podocytes and othe...