Characterization of Sigma-2 Receptor-Specific Binding Sites Using [³H]DTG and [¹²⁵I]RHM-4

• Główni autorzy: Chi-Chang Weng (Autor), Aladdin Riad (Autor), Brian P. Lieberman (Autor), Kuiying Xu (Autor), Xin Peng (Autor), John L. Mikitsh (Autor), Robert H. Mach (Autor)
• Format: Książka
• Wydane: MDPI AG, 2022-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The sigma-2 receptor/transmembrane protein 97 (σ2R/TMRM97) is a promising biomarker of tumor proliferation and a target for cancer therapy. [³H]DTG has been used to evaluate σ2R/TMEM97 binding affinity in compound development studies. However, [³H]DTG ha...