Obesity Exacerbates Lupus Activity in Fc Gamma Receptor IIb Deficient Lupus Mice Partly through Saturated Fatty Acid-Induced Gut Barrier Defect and Systemic Inflammation

• Egile Nagusiak: Kanyarat Udompornpitak (Egilea), Awirut Charoensappakit (Egilea), Kritsanawan Sae-Khow (Egilea), Thansita Bhunyakarnjanarat (Egilea), Cong Phi Dang (Egilea), Wilasinee Saisorn (Egilea), Peerapat Visitchanakun (Egilea), Pornpimol Phuengmaung (Egilea), Tanapat Palaga (Egilea), Patcharee Ritprajak (Egilea), Somkanya Tungsanga (Egilea), Asada Leelahavanichkul (Egilea)
• Formatua: Liburua
• Argitaratua: Karger Publishers, 2022-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The prevalence of obesity is increasing, and the coexistence of obesity and systemic lupus erythematosus (lupus) is possible. A high-fat diet (HFD) was orally administered for 6 months in female 8-week-old Fc gamma receptor IIb deficient (FcgRIIb−/−) lupus or age and gender-matched wild-type (WT) mi...