Genetic and non‐genetic factors influencing efavirenz population pharmacokinetics among human immunodeficiency virus‐1‐infected children in Ethiopia

• Главные авторы: Adugna Chala (Автор), Eliford Ngaimisi Kitabi (Автор), Jemal Hussien Ahmed (Автор), Birkneh Tilahun Tadesse (Автор), Tolossa Eticha Chaka (Автор), Eyasu Makonnen (Автор), Eleni Aklillu (Автор)
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• Опубликовано: Wiley, 2023-06-01T00:00:00Z.
• Предметы: article
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Abstract Despite the potential for efavirenz (EFV) to be an effective alternative antiretroviral agent, its sources of wide inter‐ and intra‐individual pharmacokinetic (PK) variability are not well‐characterized in children. We investigated the effects of genetic and non‐genetic factors, including d...